Matthew Simmonds from the School of Life Sciences will lead the next LIH Research Development Seminar entitled, Using Differences in Genetic Variants between Pancreas Transplant Donors and Recipients to Predict Long-Term Pancreas Graft Function.
Wednesday 27th September 2017, 11.45am-2pm*
Joseph Banks Laboratories – JBL0C05
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Dr Csanad Bachrati from the School of Life Sciences will lead the next LIH Research Development Seminar entitled, Maintenance of Genome Integrity in Cell Physiology and Disease.
11.45am to 2.00pm* Wednesday 26th July 2017, David Chiddick Building, Room DCB0101
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Wednesday 28th June 2017–11.45am to 2.00pm*, David Chiddick Building, Room DCB0101
Dr Enrico Ferrari from the School of Life Sciences will lead the next LIH Research Development Seminar entitled, Nanoparticles in Nanomedicine
Nanoparticles are increasingly used in medicine for the delivery of drugs, in medical imaging and in diagnostic assays. In the last decade, several types of nanoparticles have been already approved for their use in one of these three areas. This seminar will cover general aspects of nanoparticles in medicine such as the advantages and disadvantages of drug delivery using nano-carriers, some peculiar properties of materials at the nanoscale and the biological barriers that nanoparticles have to overcome to effectively reach a target in vivo.
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Wednesday 24th May 2017, 11.45am to 2.00pm, MHT Building, MC3108
Dr Louise O’Hare from the School of Psychology will lead the next LIH Research Development Seminar entitled “Temporal Integration in Migraine”.
Migraine is a common and debilitating neurological disorder. Vision is a significant component of migraine: 80% are light sensitive (Lipton et al., 2001) Headache, 41, 646-657), while for some visual stimuli can even trigger migraine attacks (Kelman, 2007, Cephalalgia, 27, 394-402). Those with migraine are consistently poorer than controls at visual tasks involving motion processing (e.g. Tibber et al., 2014, Invest. Ophthal. Vis. Sci., 55(4), 2539-46). Successful motion processing involves successful integration of signals over time. Neural oscillations (rhythmic brain activity) control the timing of information processing in the brain (Jensen et al., 2014, Trends in Neurosciences, 37(7), 357-369). In the visual areas of the brain, these are the alpha band oscillations (8-12Hz). We have pilot data showing differences between migraine and control groups in alpha band oscillations, and also poorer performance behavioural tasks involving temporal integration. Neurostimulation techniques such as transcranial alternating current stimulation (tACS) can drive neural oscillations, and this affects sensory performance (de Tommaso et al., 2014, Nat Rev Neurol, 10(3), 144-55), specifically, the integration of sensory signals over time (Cecere et al., 2015, Current Biology, 25(2), 231-235). Thus it may also be possible to influence neural oscillations using neurostimulation in those with migraine with therapeutic potential.
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Professor Martin Tovée from the School of Psychology will lead the next LIH Research Development Seminar entitled, An Interactive Training Program to treat Body Image Disturbance in Anorexia Nervosa
Wednesday 3rd May 2017, from 12.00noon to 2.00pm* in David Chiddick Building room DCB2100.
Body image disturbance is a principal diagnostic criterion for anorexia nervosa (AN), and is a key element of psychological models of this disorder. Put simply, most women with AN over-estimate body size, have negative feelings towards their body and classify lower weight bodies as fat relative to controls. This over-estimation and disparagement of body size, coupled with a morbid dread of becoming overweight, fuels a drive for thinness through abnormal eating patterns and associated behaviours. Its persistence is a predictor of the long term outcome in treatment and its continuation post-treatment is a key predictor of relapse which runs at 30% after 12 months post-treatment.
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